Definition of an efficient synthetic poly(A) site.

We constructed and analyzed a synthetic poly(A) (SPA) site that was based on the highly efficient poly(A) signal of the rabbit beta-globin gene. By use of the SPA, we demonstrate that the minimum sequences required for efficient polyadenylation are the AATAAA sequence and a GT/T-rich sequence with t...

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Bibliographic Details
Main Authors: Levitt, N, Briggs, D, Gil, A, Proudfoot, N
Format: Journal article
Language:English
Published: 1989