Deferoxamine inhibition of malaria is independent of host iron status.

The mechanism whereby deferoxamine (DF) inhibits the growth of malaria parasites was studied in rats infected with Plasmodium berghei. Peak parasitemia was 32.6% (day 14) in untreated controls and 0.15% (day 7) in rats receiving 0.33 mg/g in 8 hourly DF injections, subcutaneously. DF inhibition of p...

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Bibliographic Details
Main Authors: Hershko, C, Peto, T
Format: Journal article
Language:English
Published: 1988