Natural killer cell surveillance of intracellular antigen processing pathways mediated by recognition of HLA-E and Qa-1b by CD94/NKG2 receptors.

HLA-E binds specifically to MHC class Ia leader peptides in a TAP (transporter associated with antigen processing)-dependent manner. It interacts with CD94/NKG2A receptors on natural killer cells and this inhibits natural killer cell lysis of the cell displaying HLA-E. The crystal structure of HLA-E...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखक: O'Callaghan, C
स्वरूप: Journal article
भाषा:English
प्रकाशित: 2000