Peptide-major histocompatibility complex dimensions control proximal kinase-phosphatase balance during T cell activation.

T cell antigen recognition requires binding of the T cell receptor (TCR) to a complex between peptide antigen and major histocompatibility complex molecules (pMHC), and this recognition occurs at the interface between the T cell and the antigen-presenting cell. The TCR and pMHC molecules are small c...

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Bibliographic Details
Main Authors: Choudhuri, K, Parker, M, Milicic, A, Cole, D, Shaw, M, Sewell, A, Stewart-Jones, G, Dong, T, Gould, K, Van Der Merwe, P
Format: Journal article
Language:English
Published: 2009