Similar biological activities of two isostructural ruthenium and osmium complexes.

In this study, we probe and verify the concept of designing unreactive bioactive metal complexes, in which the metal possesses a purely structural function, by investigating the consequences of replacing ruthenium in a bioactive half-sandwich kinase inhibitor scaffold by its heavier congener osmium....

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Bibliographic Details
Main Authors: Maksimoska, J, Williams, D, Atilla-Gokcumen, G, Smalley, K, Carroll, P, Webster, R, Filippakopoulos, P, Knapp, S, Herlyn, M, Meggers, E
Format: Journal article
Language:English
Published: 2008