Initial supplementary dose of dolutegravir in second-line antiretroviral therapy: a noncomparative, double-blind, randomized placebo-controlled trial

<p><strong>Background:</strong> Dolutegravir concentrations are reduced by efavirenz induction effect necessitating twice-daily dolutegravir dosing when coadministered. Efavirenz induction persists for several weeks after stopping, which could potentially select for dolutegravir re...

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Detalhes bibliográficos
Principais autores: Zhao, Y, Griesel, R, Omar, Z, Simmons, B, Hill, A, van Zyl, G, Keene, C, Maartens, G, Meintjes, G
Formato: Journal article
Idioma:English
Publicado em: Oxford University Press 2023

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