The Role of zinc in the disulphide stress-regulated anti-sigma factor RsrA from Streptomyces coelicolor.

The regulation of disulphide stress in actinomycetes such as Streptomyces coelicolor is known to involve the zinc-containing anti-sigma factor RsrA that binds and inactivates the redox-regulated sigma factor sigmaR. However, it is not known how RsrA senses disulphide stress nor what role the metal i...

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Bibliographic Details
Main Authors: Li, W, Bottrill, A, Bibb, M, Buttner, M, Paget, MS, Kleanthous, K
Format: Journal article
Language:English
Published: 2003