A short synthesis of aphanamol I in both racemic and enantiopure forms

A short synthesis of the biologically active sesquiterpene natural product (+)-aphanamol I in both racemic and enantiopure forms is reported. Key steps include: a catalytic enantioselective conjugate addition, an oxidative radical cyclisation, and a ringexpanding Claisen rearrangement.

Bibliographic Details
Main Authors: Burton, J, Ferrara, S
Format: Journal article
Published: Wiley 2016