A short synthesis of aphanamol I in both racemic and enantiopure forms

A short synthesis of the biologically active sesquiterpene natural product (+)-aphanamol I in both racemic and enantiopure forms is reported. Key steps include: a catalytic enantioselective conjugate addition, an oxidative radical cyclisation, and a ringexpanding Claisen rearrangement.

গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Burton, J, Ferrara, S
বিন্যাস: Journal article
প্রকাশিত: Wiley 2016
বিবরন
সংক্ষিপ্ত:A short synthesis of the biologically active sesquiterpene natural product (+)-aphanamol I in both racemic and enantiopure forms is reported. Key steps include: a catalytic enantioselective conjugate addition, an oxidative radical cyclisation, and a ringexpanding Claisen rearrangement.