DNA damage induced by nitric oxide during ionizing radiation is enhanced at replication.
Nitric oxide (NO) is a very effective radiosensitizer of hypoxic mammalian cells, at least as efficient as oxygen in enhancing cell death in vitro. NO may induce cell death through the formation of base lesions which are difficult to repair, and if they occur within complex clustered damage common t...
Main Authors: | Folkes, L, O'Neill, P |
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פורמט: | Journal article |
שפה: | English |
יצא לאור: |
2013
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פריטים דומים
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DNA damage induced by nitric oxide during ionizing radiation is enhanced at replication
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Modification of DNA damage mechanisms by nitric oxide during ionizing radiation.
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Biological consequences of radiation-induced DNA damage: Relevance to radiotherapy
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Computational approach for determining the spectrum of DNA damage induced by ionizing radiation.
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