The efficiency of antigen recognition by CD8+ CTL clones is determined by the frequency of serial TCR engagement.

Using H-2Kd-restricted CTL clones, which are specific for a photoreactive derivative of the Plasmodium berghei circumsporozoite peptide PbCS(252-260) (SYIPSAEKI) and permit assessment of TCR-ligand interactions by TCR photoaffinity labeling, we have previously identified several peptide derivative v...

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Bibliographic Details
Main Authors: Hudrisier, D, Kessler, B, Valitutti, S, Horvath, C, Cerottini, J, Luescher, I
Format: Journal article
Language:English
Published: 1998