Monitoring protein-metal binding by 19F NMR – a case study with the New Delhi metallo-β-lactamase 1

19F NMR protein observed spectroscopy is evaluated as a method for analysing protein metal binding using the New Delhi metallo-β-lactamase 1. The results imply 19F NMR is useful for analysis of different metallated protein states and investigations on equilibrium states in the presence of inhibitors...

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Bibliographic Details
Main Authors: Mrs ZAHN GOWAR, Rydzik, AM, Brem, J, Chandler, SA, Benesch, JLP, Claridge, TDW, Schofield, CJ
Format: Journal article
Language:English
Published: Royal Society of Chemistry 2020