TRIM21/Ro52 - Roles in innate immunity and autoimmune disease
TRIM21 (Ro52/SSA1) is an E3 ubiquitin ligase with key roles in immune host defence, signal transduction, and possibly cell cycle regulation. It is also an autoantibody target in Sjögren’s syndrome, systemic lupus erythematosus, and other rheumatic autoimmune diseases. Here, we summarise the structur...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Frontiers Media
2021
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