Induction and maintenance of bi-functional (IFN-γ + IL-2+ and IL-2+ TNF-α+) T cell responses by DNA prime MVA boosted subtype C prophylactic vaccine tested in a Phase I trial in India

Effective vaccine design relies on accurate knowledge of protection against a pathogen, so as to be able to induce relevant and effective protective responses against it. An ideal Human Immunodeficiency virus (HIV) vaccine should induce humoral as well as cellular immune responses to prevent initial...

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Bibliographic Details
Main Authors: Munusamy Ponnan, S, Pattabiram, S, Thiruvengadam, K, Goyal, R, Singla, N, Mukherjee, J, Chatrath, S, Bergin, P, Kopycinski, J, Gilmour, J, Kumar, S, Muthu, M, Subramaniam, S, Swaminathan, S, Prasad Tripathy, S, Luke, H
Format: Journal article
Language:English
Published: Public Library of Science 2019