Successful haploidentical mismatched bone marrow transplantation in severe combined immunodeficiency: T cell removal using CAMPATH-I monoclonal antibody and E-rosetting.

Six patients with severe combined immunodeficiency were transplanted with bone marrow from their HLA haploidentical parents. T-lymphocytes were removed by complement mediated lysis with a monoclonal antibody (CAMPATH-I) followed by rosetting with sheep erythrocytes. The patients were pre-conditioned...

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Bibliographic Details
Main Authors: Morgan, G, Linch, D, Knott, LT, Davies, E, Sieff, C, Chessells, J, Hale, G, Waldmann, H, Levinsky, R
Format: Journal article
Language:English
Published: 1986