Model of a six immunoglobulin-like domain fragment of filamin A (16-21) built using residual dipolar couplings.

Filamins are actin-binding proteins that participate in a wide range of cell functions, including cell morphology, locomotion, membrane protein localization, and intracellular signaling. The three filamin isoforms found in humans, filamins A, B, and C, are highly homologous, and their roles are part...

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Bibliographic Details
Main Authors: Tossavainen, H, Koskela, O, Jiang, P, Ylänne, J, Campbell, I, Kilpeläinen, I, Permi, P
Format: Journal article
Language:English
Published: 2012