Alpha-2 macroglobulin polymorphism and Alzheimer disease risk in the UK.

There is a genetic component in the aetiology of Alzheimer disease1 (AD). Recently, Blacker et al. reported an odds ratio of 3.56 for being affected by AD in individuals carrying at least one copy of an -2 macroglobulin gene (A2M) allele (A2M*2) corresponding to a deletion near the 5andacute; splice...

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Bibliographic Details
Main Authors: Dow, D, Lindsey, N, Cairns, N, Brayne, C, Robinson, D, Huppert, F, Paykel, E, Xuereb, J, Wilcock, G, Whittaker, J, Rubinsztein, D
Format: Journal article
Language:English
Published: 1999