Preclinical murine tumor models: a structural and functional perspective

The goal of this review is to pinpoint the specific features, including the weaknesses, of various tumor models, and to discuss the reasons why treatments that are efficient in murine tumor models often do not work in clinics. In a detailed comparison of transplanted and spontaneous tumor models, we...

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Bibliographic Details
Main Authors: Guerin, MV, Finisguerra, V, Van den Eynde, BJ, Bercovici, N, Trautmann, T
Format: Journal article
Language:English
Published: eLife Sciences Publications, Ltd 2020