Preclinical murine tumor models: a structural and functional perspective

Preclinical murine tumor models: a structural and functional perspective

The goal of this review is to pinpoint the specific features, including the weaknesses, of various tumor models, and to discuss the reasons why treatments that are efficient in murine tumor models often do not work in clinics. In a detailed comparison of transplanted and spontaneous tumor models, we...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy:	Guerin, MV, Finisguerra, V, Van den Eynde, BJ, Bercovici, N, Trautmann, T
Format:	Journal article
Język:	English
Wydane:	eLife Sciences Publications, Ltd 2020

Podobne zapisy

Preclinical murine tumor models: A structural and functional perspective
od: Marion V Guerin, i wsp.
Wydane: (2020-01-01)

Enhanced tumor response to adoptive T cell therapy with PHD2/3-deficient CD8 T cells
od: Dvorakova, T, i wsp.
Wydane: (2024)

Metformin improves cancer immunotherapy by directly rescuing tumor-infiltrating CD8 T lymphocytes from hypoxia-induced immunosuppression
od: Finisguerra, V, i wsp.
Wydane: (2023)

The Remarkable Plasticity of Macrophages: A Chance to Fight Cancer
od: Nadège Bercovici, i wsp.
Wydane: (2019-07-01)

Arid5a: A missing link between EMT and tumoral immune resistance
od: Van den Eynde, BJ
Wydane: (2021)

TGFβ blocks IFNα/β release and tumor rejection in spontaneous mammary tumors
od: Marion V. Guerin, i wsp.
Wydane: (2019-09-01)

Tryptophan 2,3-dioxygenase expression identified in murine decidual stromal cells is not essential for feto-maternal tolerance
od: Hoffmann, D, i wsp.
Wydane: (2020)

Enhanced tumor response to adoptive T cell therapy with PHD2/3-deficient CD8 T cells
od: Tereza Dvorakova, i wsp.
Wydane: (2024-09-01)

Metformin improves cancer immunotherapy by directly rescuing tumor-infiltrating CD8 T lymphocytes from hypoxia-induced immunosuppression
od: Benoit J Van den Eynde, i wsp.
Wydane: (2023-05-01)

Local IFNα enhances the anti-tumoral efficacy of systemic anti-PD1 to prevent tumor relapse
od: Maxime Thoreau, i wsp.
Wydane: (2020-10-01)

Functional differences between proteasome subtypes
od: Abi Habib, J, i wsp.
Wydane: (2022)

Novel preclinical murine model of trauma-induced elbow stiffness
od: Stephanie N. Moore-Lotridge, i wsp.
Wydane: (2018-09-01)

Combining personalized neoantigen vaccination with chemotherapy and anti-PD-1 to treat NSCLC
od: Leung, CSK, i wsp.
Wydane: (2022)

Tryptophan-degrading enzymes in tumoral immune resistance
od: Nicolas van Baren, i wsp.
Wydane: (2016-11-01)

Tryptophan 2,3-Dioxygenase Expression Identified in Murine Decidual Stromal Cells Is Not Essential for Feto-Maternal Tolerance
od: Delia Hoffmann, i wsp.
Wydane: (2020-12-01)

TGFβ1 neutralization displays therapeutic efficacy through both an immunomodulatory and a non-immune tumor-intrinsic mechanism
od: Canè, S, i wsp.
Wydane: (2021)

Combining Photodynamic Therapy with Immunostimulatory Nanoparticles Elicits Effective Anti-Tumor Immune Responses in Preclinical Murine Models
od: Ruben Victor Huis in ‘t Veld, i wsp.
Wydane: (2021-09-01)

Circulating tumor cell-derived preclinical models: current status and future perspectives
od: Zuzana Kahounová, i wsp.
Wydane: (2023-08-01)

The STING agonist DMXAA triggers a cooperation between T lymphocytes and myeloid cells that leads to tumor regression
od: Julia M. Weiss, i wsp.
Wydane: (2017-10-01)

Constitutive IDO1 expression in human tumors is driven by cyclooxygenase-2 and mediates intrinsic immune resistance
od: Hennequart, M, i wsp.
Wydane: (2017)

A Novel Preclinical Murine Model of Systemic Lupus Erythematosus–Like Cardiovascular Disease
od: Marice K. McCrorey, i wsp.
Wydane: (2024-12-01)

Editorial: Heme proteins: key players in the regulation of immune responses
od: Volpi, C, i wsp.
Wydane: (2023)

Uncovering molecular actors of IDO-mediated T cell dysfunction with genome-wide CRISPR/Cas9 knockout screens
od: Bombart, R, i wsp.
Wydane: (2022)

A 31-plex panel for high-dimensional single-cell analysis of murine preclinical models of solid tumors by imaging mass cytometry
od: Yaël Glasson, i wsp.
Wydane: (2023-01-01)

Correction: Circulating tumor cell-derived preclinical models: current status and future perspectives
od: Zuzana Kahounová, i wsp.
Wydane: (2024-07-01)

Systemic tryptophan homeostasis
od: Klaessens, S, i wsp.
Wydane: (2022)

MRI and MRS alterations in the preclinical phase of murine prion disease: association with neuropathological and behavioural changes.
od: Broom, K, i wsp.
Wydane: (2007)

Apoptosis of tumor-infiltrating T lymphocytes: a new immune checkpoint mechanism
od: Zhu, J, i wsp.
Wydane: (2018)

Secondary Ischemia Assessment in Murine and Rat Preclinical Subarachnoid Hemorrhage Models: A Systematic Review
od: Elias Fürstenau, i wsp.
Wydane: (2024-03-01)

Preclinical Activity of Two Paclitaxel Nanoparticle Formulations After Intraperitoneal Administration in Ovarian Cancer Murine Xenografts
od: Demuytere J, i wsp.
Wydane: (2024-01-01)

MRI and MRS alterations in the preclinical phase of murine prion disease: Association with neuropathological and behavioural changes
od: Kerry A. Broom, i wsp.
Wydane: (2007-06-01)

Editorial: Inhibitors of CDK family: New perspective and rationale for drug combination in preclinical models of solid tumors
od: Andrea Cavazzoni, i wsp.
Wydane: (2023-03-01)

Characterization of retinal function and structure in the MPTP murine model of Parkinson’s disease
od: Katie K. N. Tran, i wsp.
Wydane: (2022-05-01)

Preclinical Models of Pediatric Brain Tumors—Forging Ahead
od: Tara H.W. Dobson, i wsp.
Wydane: (2018-10-01)

Preclinical Ward Teaching Student's Perspective
od: Tehreem Fatima, i wsp.
Wydane: (2014-06-01)

Trophic and immunomodulatory effects of adipose tissue derived stem cells in a preclinical murine model of endometriosis
od: Toyofumi Hirakawa, i wsp.
Wydane: (2022-05-01)

In Vivo Murine-Matured Human CD3+ Cells as a Preclinical Model for T Cell-Based Immunotherapies
od: Kevin G. Haworth, i wsp.
Wydane: (2017-09-01)

Preclinical Evaluation of Anti-HIV-1 Polybiguanide Vaginal Microbicides in a Murine Model of Toxicity and Inflammation
od: Krebs Fred C, i wsp.
Wydane: (2005-12-01)

Blood–Brain Barrier Dysfunction in Mild Traumatic Brain Injury: Evidence From Preclinical Murine Models
od: Yingxi Wu, i wsp.
Wydane: (2020-08-01)

Photoacoustic-based oxygen saturation assessment of murine femoral bone marrow in a preclinical model of leukemia
od: Cayla Wood, i wsp.
Wydane: (2019-06-01)