Human antibody C10 neutralizes by diminishing Zika but enhancing dengue virus dynamics

The human monoclonal antibody (HmAb) C10 potently cross-neutralizes Zika virus (ZIKV) and dengue virus. Analysis of antibody fragment (Fab) C10 interactions with ZIKV and dengue virus serotype 2 (DENV2) particles by cryoelectron microscopy (cryo-EM) and amide hydrogen/deuterium exchange mass spectro...

Full description

Bibliographic Details
Main Authors: Lim, X-X, Shu, B, Zhang, S, Tan, AWK, Ng, T-S, Lim, X-N, Chew, VS-Y, Shi, J, Screaton, GR, Lok, S-M, Anand, GS
Format: Journal article
Language:English
Published: Cell Press 2021