Oxidation by 2-oxoglutarate oxygenases: non-haem iron systems in catalysis and signalling.
The 2-oxoglutarate (2OG) and ferrous iron dependent oxygenases are a superfamily of enzymes that catalyse a wide range of reactions including hydroxylations, desaturations and oxidative ring closures. Recently, it has been discovered that they act as sensors in the hypoxic response in humans and oth...
Автори: | Hewitson, K, Granatino, N, Welford, R, McDonough, M, Schofield, C |
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Формат: | Journal article |
Мова: | English |
Опубліковано: |
2005
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