The aorta can act as a site of naıve CD41 T-cell priming

Aims - Aortic adaptive immunity plays a crucial role in atherosclerosis; however, the precise mechanisms leading to T cell activation in the arterial wall remain poorly understood. Methods and Results - Here we have identified naïve T cells in the aorta of wild-type and TCR transgenic mice and we d...

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Bibliographic Details
Main Authors: Macritchie, N, Grassia, G, Noonan, J, Cole, J, Hughes, C, Schroeder, J, Benson, R, Cochain, C, Zernecke, A, Guzik, T, Monaco, C, Garside, P, Maffia, P
Format: Journal article
Published: Oxford University Press 2019