α-Synuclein and dopamine at the crossroads of Parkinson's disease.
α-Synuclein is central to the Lewy body neuropathology of Parkinson's disease (PD), a devastating neurodegenerative disorder characterized by numerous motor and non-motor manifestations. The cardinal motor symptoms are linked to death of dopaminergic neurons in the nigrostriatal pathway. Here w...
Main Authors: | , , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2010
|