Control of anterior GRadient 2 (AGR2) dimerization links endoplasmic reticulum proteostasis to inflammation

Anterior gradient 2 (AGR2) is a dimeric protein disulfide isomerase family member involved in the regulation of protein quality control in the endoplasmic reticulum (ER). Mouse AGR2 deletion increases intestinal inflammation and promotes the development of inflammatory bowel disease (IBD). Although...

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Main Authors: Maurel, M, Obacz, J, Avril, T, Ding, Y-P, Papadodima, O, Treton, X, Daniel, F, Pilalis, E, Hörberg, J, Hou, W, Beauchamp, M-C, Tourneur-Marsille, J, Cazals-Hatem, D, Sommerova, L, Samali, A, Tavernier, J, Hrstka, R, Dupont, A, Fessart, D, Delom, F, Fernandez-Zapico, ME, Jansen, G, Eriksson, LA, Thomas, DY, Jerome-Majewska, L, Hupp, T, Chatziioannou, A, Chevet, E, Ogier-Denis, E
Format: Journal article
Language:English
Published: Wiley Open Access 2019