The role of transposable elements in the regulation of IFN-lambda1 gene expression.

IFNs lambda1, lambda2, and lambda3, or type III IFNs, are recently identified cytokines distantly related to type I IFNs. Despite an early evolutionary divergence, the 2 types of IFNs display similar antiviral activities, and both are produced primarily in dendritic cells. Although virus induction o...

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Bibliographic Details
Main Authors: Thomson, S, Goh, F, Banks, H, Krausgruber, T, Kotenko, S, Foxwell, B, Udalova, I
Format: Journal article
Language:English
Published: 2009