An expanding job description for Blimp-1/PRDM1.
The master transcriptional regulator Blimp-1/PRDM1 contains an N-terminal PR/SET domain and five C2H2 zinc fingers located near its C-terminus that mediate DNA binding, nuclear import and recruitment of histone modifying enzymes. These activities account for its ability to control cell-fate decision...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2009
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