Basal localization of MT1-MMP is essential for epithelial cell morphogenesis in 3D collagen matrix

The membrane-anchored collagenase membrane type 1 matrix metalloprotease (MT1-MMP) has been shown to play an essential role during epithelial tubulogenesis in 3D collagen matrices; however, its regulation during tubulogenesis is not understood. Here, we report that degradation of collagen in polariz...

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Dettagli Bibliografici
Autori principali: Weaver, SA, Wolters, B, Ito, N, Woskowicz, A, Kaneko, K, Shitomi, Y, Seiki, M, Itoh, Y
Natura: Journal article
Lingua:English
Pubblicazione: Company of Biologists 2014