Severe malaria is associated with a deficiency of von Willebrand factor cleaving protease, ADAMTS13.

Severe falciparum malaria remains a major killer in tropical countries. Central in the pathophysiology is mechanical obstruction in the microcirculation caused by cytoadherence and sequestration of parasitized erythrocytes. However, the pathogenesis of many features complicating severe malaria, incl...

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Bibliographic Details
Main Authors: Löwenberg, E, Charunwatthana, P, Cohen, S, van den Born, B, Meijers, J, Yunus, E, Hassan, M, Hoque, G, Maude, R, Nuchsongsin, F, Levi, M, Dondorp, A
Format: Journal article
Language:English
Published: 2010