Using an experimental medicine model to understand the antidepressant potential of the N-Methyl-D-aspartic acid (NMDA) receptor antagonist memantine.

There is growing interest in the role of the glutamatergic system both in depression and as a novel target for treatments. Preclinical studies suggested that the non-competitive N-Methyl-D-aspartic acid (NMDA) receptor antagonist memantine might have antidepressant properties, but a randomised contr...

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Những tác giả chính: Pringle, A, Parsons, E, Cowen, L, McTavish, S, Cowen, P, Harmer, C
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2012