Bone spicule pigment formation in retinitis pigmentosa: insights from a mouse model.

BACKGROUND: Bone spicule pigments (BSP) are a hallmark of retinitis pigmentosa (RP). In this study, we examined the process of BSP formation in the rhodopsin knockout (rho (-/-)) mouse, a murine model for human RP. METHODS: In rho (-/-) mice from 2 to 16 months of age, representing the range from e...

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Bibliographic Details
Main Authors: Jaissle, G, May, C, van de Pavert, SA, Wenzel, A, Claes-May, E, Giessl, A, Szurman, P, Wolfrum, U, Wijnholds, J, Fischer, M, Fisher, MD, Humphries, P, Seeliger, M
Format: Journal article
Language:English
Published: 2010