KATP channel mutation disrupts hippocampal network activity and nocturnal gamma shifts

KATP channel mutation disrupts hippocampal network activity and nocturnal gamma shifts

ATP-sensitive potassium (KATP) channels couple cell metabolism to cellular electrical activity. Humans affected by severe activating mutations in KATP channels suffer from developmental delay, epilepsy, and neonatal diabetes (DEND syndrome). While the aetiology of diabetes in DEND syndrome is well u...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Burkart, M-E, Kurzke, J, Jacobi, R, Vera, J, Ashcroft, FM, Eilers, J, Lippmann, K
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	Oxford University Press 2024

Eitemau Tebyg

Neonatal diabetes and the KATP channel: From mutation to therapy.
gan: Ashcroft, FM, et al.
Cyhoeddwyd: (2017)

Direct interaction of Na-azide with the KATP channel.
gan: Trapp, S, et al.
Cyhoeddwyd: (2000)

Effects of activating KATP channel mutations on neuronal function
gan: McTaggart, J, et al.
Cyhoeddwyd: (2011)

KATP channels and the metabolic regulation of insulin secretion in health and disease: the 2022 Banting Medal for Scientific Achievement Award Lecture
gan: Ashcroft, FM
Cyhoeddwyd: (2023)

Ketones prevent oxidative impairment of hippocampal synaptic integrity through KATP channels.
gan: Do Young Kim, et al.
Cyhoeddwyd: (2015-01-01)

Characterisation of new KATP-channel mutations associated with congenital hyperinsulinism in the Finnish population.
gan: Reimann, F, et al.
Cyhoeddwyd: (2003)

Muscle dysfunction caused by a KATP channel mutation in neonatal diabetes is neuronal in origin.
gan: Clark, R, et al.
Cyhoeddwyd: (2010)

Molecular determinants of KATP channel inhibition by ATP.
gan: Tucker, S, et al.
Cyhoeddwyd: (1998)

KATP channels and islet hormone secretion: New insights and controversies
gan: Ashcroft, F, et al.
Cyhoeddwyd: (2013)

Phentolamine block of KATP channels is mediated by Kir6.2.
gan: Proks, P, et al.
Cyhoeddwyd: (1997)

Keeping the heart going: a new role for KATP channels.
gan: Tammaro, P, et al.
Cyhoeddwyd: (2006)

Nucleotide modulation of pinacidil stimulation of cloned KATP channels
gan: Reimann, F, et al.
Cyhoeddwyd: (2000)

KATP channels and cardioprotection
gan: Taskin Eylem, et al.
Cyhoeddwyd: (2024-01-01)

Functional effects of naturally occurring KCNJ11 mutations causing neonatal diabetes on cloned cardiac KATP channels.
gan: Tammaro, P, et al.
Cyhoeddwyd: (2006)

Binding of sulphonylureas to plasma proteins – a KATP channel perspective
gan: Proks, P, et al.
Cyhoeddwyd: (2018)

The KATP and Kv channels are distinct entities: a reply to Edwards and Weston.
gan: Ashcroft, F, et al.
Cyhoeddwyd: (1994)

Binding of sulphonylureas to plasma proteins - A KATP channel perspective.
gan: Peter Proks, et al.
Cyhoeddwyd: (2018-01-01)

The role of the KATP channel in glucose homeostasis in health and disease: more than meets the islet.
gan: McTaggart, J, et al.
Cyhoeddwyd: (2010)

Regulation of KATP channel activity
gan: Usher, S
Cyhoeddwyd: (2021)

Evidence for a KATP Channel in Rough Endoplasmic Reticulum (rerKATP Channel) of Rat Hepatocytes.
gan: Sajjad Salari, et al.
Cyhoeddwyd: (2015-01-01)

A mutation in the ATP-binding site of the Kir6.2 subunit of the KATP channel alters coupling with the SUR2A subunit.
gan: Tammaro, P, et al.
Cyhoeddwyd: (2007)

The Kir6.2-F333I mutation differentially modulates KATP channels composed of SUR1 or SUR2 subunits.
gan: Tammaro, P, et al.
Cyhoeddwyd: (2007)

Involvement of the N-terminus of Kir6.2 in the inhibition of the KATP channel by ATP.
gan: Proks, P, et al.
Cyhoeddwyd: (1999)

Mapping the architecture of the ATP-binding site of the KATP channel subunit Kir6.2.
gan: Dabrowski, M, et al.
Cyhoeddwyd: (2004)

MgATP activates the beta cell KATP channel by interaction with its SUR1 subunit.
gan: Gribble, F, et al.
Cyhoeddwyd: (1998)

Altered functional properties of KATP channel conferred by a novel splice variant of SUR1.
gan: Sakura, H, et al.
Cyhoeddwyd: (1999)

Functional analysis of a structural model of the ATP-binding site of the KATP channel Kir6.2 subunit.
gan: Antcliff, J, et al.
Cyhoeddwyd: (2005)

Pyridine nucleotide regulation of the KATP channel Kir6.2/SUR1 expressed in Xenopus oocytes.
gan: Dabrowski, M, et al.
Cyhoeddwyd: (2003)

KATP channel mutations in congenital hyperinsulinism: Progress and challenges towards mechanism-based therapies
gan: Assmaa ElSheikh, et al.
Cyhoeddwyd: (2023-03-01)

KATP channel dependent heart multiome atlas
gan: D. Kent Arrell, et al.
Cyhoeddwyd: (2022-05-01)

PIP2 and PIP as determinants for ATP inhibition of KATP channels.
gan: Baukrowitz, T, et al.
Cyhoeddwyd: (1998)

A cytosolic factor that inhibits KATP channels expressed in Xenopus oocytes by impairing Mg-nucleotide activation by SUR1.
gan: Tammaro, P, et al.
Cyhoeddwyd: (2009)

Structure based analysis of KATP channel with a DEND syndrome mutation in murine skeletal muscle
gan: Shoichiro Horita, et al.
Cyhoeddwyd: (2021-03-01)

A universally conserved residue in the SUR1 subunit of the KATP channel is essential for translating nucleotide binding at SUR1 into channel opening.
gan: De Wet, H, et al.
Cyhoeddwyd: (2012)

Do KATP channels have a role in immunity?
gan: Stefan Feske, et al.
Cyhoeddwyd: (2024-11-01)

The Structural Basis for the Binding of Repaglinide to the Pancreatic KATP Channel
gan: Dian Ding, et al.
Cyhoeddwyd: (2019-05-01)

Expression of an activating mutation in the gene encoding the KATP channel subunit Kir6.2 in mouse pancreatic beta cells recapitulates neonatal diabetes.
gan: Girard, C, et al.
Cyhoeddwyd: (2009)

SUBSTRATE-DEPENDENT CHANGES IN MITOCHONDRIAL-FUNCTION, [CA-2+]I AND KATP CHANNELS IN MOUSE PANCREATIC BETA-CELLS INVITRO
gan: Duchen, M, et al.
Cyhoeddwyd: (1993)

Mutations of the same conserved glutamate residue in NBD2 of the sulfonylurea receptor 1 subunit of the KATP channel can result in either hyperinsulinism or neonatal diabetes.
gan: Männikkö, R, et al.
Cyhoeddwyd: (2011)

Inward rectification in KATP channels: a pH switch in the pore.
gan: Baukrowitz, T, et al.
Cyhoeddwyd: (1999)