High-throughput sequencing provides insights into genome variation and evolution in Salmonella Typhi.

Isolates of Salmonella enterica serovar Typhi (Typhi), a human-restricted bacterial pathogen that causes typhoid, show limited genetic variation. We generated whole-genome sequences for 19 Typhi isolates using 454 (Roche) and Solexa (Illumina) technologies. Isolates, including the previously sequenc...

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Bibliographic Details
Main Authors: Holt, K, Parkhill, J, Mazzoni, C, Roumagnac, P, Weill, F, Goodhead, I, Rance, R, Baker, S, Maskell, D, Wain, J, Dolecek, C, Achtman, M, Dougan, G
Format: Journal article
Language:English
Published: 2008