Stress-activated kinase MKK7 governs epigenetics of cardiac repolarization for arrhythmia prevention
BACKGROUND: -Ventricular arrhythmia is a leading cause of cardiac mortality. Most antiarrhythmics present paradoxical pro-arrhythmic side effects, culminating in a greater risk of sudden death. METHODS: -We describe a new regulatory mechanism linking mitogen-activated kinase kinase-7 (MKK7) deficien...
Main Authors: | , , , , , , , , , , , , , , , , , , , , , , |
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פורמט: | Journal article |
שפה: | English |
יצא לאור: |
American Heart Association
2016
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