Stress-activated kinase MKK7 governs epigenetics of cardiac repolarization for arrhythmia prevention

BACKGROUND: -Ventricular arrhythmia is a leading cause of cardiac mortality. Most antiarrhythmics present paradoxical pro-arrhythmic side effects, culminating in a greater risk of sudden death. METHODS: -We describe a new regulatory mechanism linking mitogen-activated kinase kinase-7 (MKK7) deficien...

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Bibliographic Details
Main Authors:	Chowdhury, S, Liu, W, Zi, M, Li, Y, Wang, S, Tsui, H, Prehar, S, Castro, S, Zhang, H, Ji, Y, Zhang, X, Xiao, R, Zhang, R, Lei, M, Cyganek, L, Guan, K, Millar, C, Liao, X, Jain, M, Boyett, M, Cartwright, E, Shiels, H, Wang, X
Format:	Journal article
Language:	English
Published:	American Heart Association 2016

Stress-activated kinase MKK7 governs epigenetics of cardiac repolarization for arrhythmia prevention

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