Significance of DNA polymerase I in in vivo processing of clustered DNA damage

We examined the biological consequences of bi-stranded clustered damage sites, consisting of a combination of DNA lesions, such as a 1-nucleotide gap (GAP), an apurinic/apyrimidinic (AP) site, and an 8-oxo-7,8-dihydroguanine (8-oxoG), using a bacterial plasmid-based assay. Following transformation w...

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Bibliographic Details
Main Authors: Shikazono, N, Akamatsu, K, Takahashi, M, Noguchi, M, Urushibara, A, O'Neill, P, Yokoya, A
Format: Journal article
Language:English
Published: 2013