Numbers needed to treat calculated from responder rates give a better indication of efficacy in osteoarthritis trials than mean pain scores
Introduction: Osteoarthritis trials usually report average changes in visual analogue scale (VAS) pain, and examine the difference between treatment and placebo. We investigated whether dichotomous responder analysis provides a more informative interpretation of drug efficacy. Methods: Merck supplie...
Main Authors: | , , , |
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Format: | Journal article |
Language: | English |
Published: |
BioMed Central
2008
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Subjects: |