Asymmetric synthesis of the tetraponerine alkaloids

The asymmetric syntheses of all eight tetraponerine alkaloids (T1–T8) were achieved using the diastereoselective conjugate additions of lithium amide reagents in the key stereodefining steps. Conjugate addition of either lithium (R)-N-allyl-N-(α-methylbenzyl)amide or lithium (R)-N-(but-3-en-1-yl)-N-...

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Bibliographic Details
Main Authors: Davies, S, Fletcher, A, Houlsby, I, Roberts, P, Thomson, J
Format: Journal article
Published: American Chemical Society 2017