HPS2-THRIVE randomized placebo-controlled trial in 25 673 high-risk patients of ER niacin/laropiprant: trial design, pre-specified muscle and liver outcomes, and reasons for stopping study treatment.

<p><strong>Aims</strong>Niacin has potentially favourable effects on lipids, but its effect on cardiovascular outcomes is uncertain. HPS2-THRIVE is a large randomized trial assessing the effects of extended release (ER) niacin in patients at high risk of vascular events.</p>&...

Full description

Bibliographic Details
Main Authors: HPS2-THRIVE Collaborative Group, Jiang, L, Hopewell, J, Collins, R, Armitage, J
Format: Journal article
Language:English
Published: Oxford University Press 2013