Synchronised spiking activity underlies phase amplitude coupling in the subthalamic nucleus of Parkinson's disease patients
Both phase-amplitude coupling (PAC) and beta-bursts in the subthalamic nucleus have been significantly linked to symptom severity in Parkinson's disease (PD) in humans and emerged independently as competing biomarkers for closed-loop deep brain stimulation (DBS). However, the underlying nature...
Main Authors: | Meidahl, A, Moll, C, Van Wijk, B, Gulberti, A, Tinkhauser, G, Westphal, M, Engel, A, Hamel, W, Brown, P, Sharott, A |
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Format: | Journal article |
Language: | English |
Published: |
Elsevier
2019
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