Strong interferon-gamma mediated cellular immunity to scrub typhus demonstrated using a novel whole cell antigen ELISpot assay in rhesus macaques and humans
Scrub typhus is a febrile infection caused by the obligate intracellular bacterium Orientia tsutsugamushi, which causes significant morbidity and mortality across the Asia-Pacific region. The control of this vector-borne disease is challenging due to humans being dead-end hosts, vertical maintenance...
| Autors principals: | , , , , , , , , , , , , , , , , , , , |
|---|---|
| Altres autors: | |
| Format: | Journal article |
| Idioma: | English |
| Publicat: |
Public Library of Science
2017
|