A proteomic analysis of changes in prothrombin and plasma proteins associated with the G20210A mutation.

The G-->A mutation at position 20210 of the prothrombin gene, localized in the 3'-polyadenylation untranslated region of the mRNA, is a recognized genetic risk factor for venous thromboembolism. The mechanism by which this base change confers an increased risk of thrombosis compared to n...

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Main Authors: Gelfi, C, Viganò, A, Ripamonti, M, Wait, R, Begum, S, Biguzzi, E, Castaman, G, Faioni, E
格式: Journal article
语言:English
出版: 2004