Airway proteomics reveals broad residual anti-inflammatory effects of prednisolone in mepolizumab-treated asthma

<p><b>Background</b></p> Mepolizumab is an anti-interleukin-5 monoclonal antibody treatment for severe eosinophilic asthma (SEA) that reduces asthma exacerbations. Residual airway inflammation on mepolizumab may lead to persistent exacerbations. Oral corticosteroids remain th...

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Main Authors: Howell, I, Yang, F, Brown, V, Cane, J, Marchi, E, Azim, A, Busby, J, McDowell, PJ, Diver, SE, Borg, C, Heaney, LG, Pavord, ID, Brightling, CE, Chaudhuri, R, Hinks, TSC
Format: Journal article
Jezik:English
Izdano: Elsevier 2024