Investigation of the potential mechanisms underlying nuclear F-actin organization in ovarian cancer cells by high-throughput screening in combination with deep learning

Increasing evidence supports the notion that filamentous actin (F-actin) and globular actin exist in the nuclei of somatic cells, and are involved in chromatin remodeling, gene transcription regulation and DNA damage repair. However, the underlying mechanisms of how nuclear F-actin are polymerized i...

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Bibliographic Details
Main Authors: Wu, X, Xing, X, Wang, M, Feng, Y, Wietek, N, Chong, K, El-Sahhar, S, Ahmed, AA, Zang, R, Zeng, Y
Format: Journal article
Language:English
Published: Frontiers Media 2022