FORMATION OF A NOVEL BICYCLIC GAMMA-LACTAM WITH ISOPENICILLIN-N SYNTHASE
Incubation of isopenicillin N synthase (IPNS) with [(5S)-5-amino-5- carboxypentanoyl]-L- homocysteinyl-L-cysteine (14) resulted in the formation of a novel bicyclic γ-lactam (17) containing an intramolecular disulphide linkage.
প্রধান লেখক: | , , , |
---|---|
বিন্যাস: | Journal article |
ভাষা: | English |
প্রকাশিত: |
1989
|