Mutation patterns of 16 genes in primary and secondary acute myeloid leukemia (AML) with normal cytogenetics

Acute myeloid leukemia patients with normal cytogenetics (CN-AML) account for almost half of AML cases. We aimed to study the frequency and relationship of a wide range of genes previously reported as mutated in AML (ASXL1, NPM1, FLT3, TET2, IDH1/2, RUNX1, DNMT3A, NRAS, JAK2, WT1, CBL, SF3B1, TP53,...

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Bibliographic Details
Main Authors: Fernandez-Mercado, M, Yip, B, Pellagatti, A, Davies, C, Larrayoz, M, Kondo, T, Pérez, C, Killick, S, McDonald, E, Odero, MD, Agirre, X, Prósper, F, Calasanz, M, Wainscoat, J, Boultwood, J
Format: Journal article
Language:English
Published: Public Library of Science 2012