ATP-sensitive potassium channels in health and disease

The ATP-sensitive potassium (KATP) channel plays a crucial role in insulin secretion and thus glucose homeostasis. KATP channel activity in the pancreatic β-cell is finely balanced; increased activity prevents insulin secretion, whereas reduced activity stimulates insulin release. β-cell metabolism...

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Bibliographic Details
Main Authors: Proks, P, Clarke, R
Other Authors: Islam, M
Format: Book section
Published: Springer Netherlands 2014