ATP-sensitive potassium channels in health and disease
The ATP-sensitive potassium (KATP) channel plays a crucial role in insulin secretion and thus glucose homeostasis. KATP channel activity in the pancreatic β-cell is finely balanced; increased activity prevents insulin secretion, whereas reduced activity stimulates insulin release. β-cell metabolism...
Main Authors: | Proks, P, Clarke, R |
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Other Authors: | Islam, M |
Format: | Book section |
Published: |
Springer Netherlands
2014
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