Sequential open-label study of the safety, tolerability, and pharmacokinetic interactions between dihydroartemisinin-piperaquine and mefloquine in healthy Thai adults

Sequential open-label study of the safety, tolerability, and pharmacokinetic interactions between dihydroartemisinin-piperaquine and mefloquine in healthy Thai adults

Artemisinin-based combination therapies (ACTs) have contributed substantially to the global decline in Plasmodium falciparum morbidity and mortality, but resistance to artemisinins and their partner drugs is increasing in Southeast Asia, threatening malaria control. New antimalarial compounds will n...

Полное описание

Библиографические подробности
Главные авторы:	Hanboonkunupakarn, B, Van Der Pluijm, R, Hoglund, R, Pukrittayakamee, S, Winterberg, M, Mukaka, M, Waithira, N, Chotivanich, K, Singhasivanon, P, White, N, Dondorp, A, Tarning, J, Jittamala, P
Формат:	Journal article
Язык:	English
Опубликовано:	American Society for Microbiology 2019

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