The role of the C-terminus of SUR in the differential regulation of beta-cell and cardiac KATP channels by MgADP and metabolism

ATP‐sensitive potassium (KATP) channels couple the metabolic state of a cell to its electrical activity and play important physiological roles in many tissues. In contrast to β‐cell (Kir6.2/SUR1) channels, which open when extracellular glucose levels fall, cardiac (Kir6.2/SUR2A) channels remain clos...

Full description

Bibliographic Details
Main Authors: Vedovato, N, Rorsman, O, Hennis, K, Ashcroft, F, Proks, P
Format: Journal article
Published: John Wiley & Sons, Inc 2018