The role of the C-terminus of SUR in the differential regulation of beta-cell and cardiac KATP channels by MgADP and metabolism
ATP‐sensitive potassium (KATP) channels couple the metabolic state of a cell to its electrical activity and play important physiological roles in many tissues. In contrast to β‐cell (Kir6.2/SUR1) channels, which open when extracellular glucose levels fall, cardiac (Kir6.2/SUR2A) channels remain clos...
Main Authors: | Vedovato, N, Rorsman, O, Hennis, K, Ashcroft, F, Proks, P |
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Format: | Journal article |
Published: |
John Wiley & Sons, Inc
2018
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